Fig. 3

Mutation profile for the WW22-4017 poliovirus isolate. (A) Nucleotide and (B) amino acid mutation profiles of WW22-4017 (PQ641085) as compared to Sabin 2 (AY184220.1), USA-NY-22 (OP265178.1) and London UK environmental sample (OP410366.1). Mutations resulting in enhanced neurovirulence are depicted. UTR = untranslated region; P1 = polyprotein 1; VP1 = viral protein 1; P2 = polyprotein 2; P3 = polyprotein 3; WW = wastewater.