Table 1 pSLE patient data used in the development and training of Morgaf and its digitalization.
Parameters | Learning criterion | Learning inputs | Outputs | Presence in the patient |
|---|---|---|---|---|
Sociodemographic data | ||||
Age at diagnosis | Year; numeric value | Numeric | Numeric | Mandatory |
Organ involvement at the time of diagnosis | ||||
Skin | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Renal | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Bone Marrow | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Central Nervous System | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Joint(s) | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Liver | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Presence of painless aphthae | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Presence of serositis | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Eye | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Intestinal | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Systolic blood pressure (mm Hg) | 80–110 is normal. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Not mandatory |
Diastolic blood pressure (mm Hg) | 60–80 is normal. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Not mandatory |
Laboratory results at the time of diagnosis | ||||
Hemoglobin (gr/dL) | Typical range: 13–17. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Mandatory |
Leukocyte (/mm3) | Typical range: 5000–13,200. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Mandatory |
Lymphocyte value (/mm3) | Typical range: 2000–6000. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Mandatory |
Neutrophil value (/mm3) | Typical range: 2000–8300. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Mandatory |
Platelet value (/mm3) | Typical range: 190,000–400,000. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Mandatory |
CRP value (mg/dL) | Typical range: 0–0,5. Other parameters are abnormal | 0 and 1 | from 0 to 1 | Not mandatory |
ESR value (mm/h) | Typical range: 0–20. Other parameters are abnormal | 0 and 1 | from 0 to 1 | Not mandatory |
Urine density | Typical range: 1003–1020. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Not mandatory |
Presence of hematuria in urine | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Presence of ketones in urine | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Presence of pyuria in urine | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
Presence of proteinuria in urine | Yes/No | 0 and 1 | from 0 to 1 | Not mandatory |
BUN (mg/dL) | Typical range: 5–18. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Not mandatory |
Creatinine (mg/dL) | Typical range: 0,5–1,2. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Not mandatory |
Complement C3 (mg/dL) | Typical range: 88–230. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Mandatory |
Complement C4 (mg/dL) | Typical range: 13–73. Other parameters are abnormal | − 1, 0 and 1 | from 0 to 1 | Mandatory |
ANA | If titer is < 1/40: negative, > 1/40 is positive | 0 and 1 | from 0 to 1 | Mandatory |
Anti-ds-DNA (IU/mL) | Typical range: 0–5. Other parameters are abnormal | 0 and 1 | from 0 to 1 | Mandatory |
B2GPA IgG (U/mL) | Typical expect result is zero. Other parameters are abnormal | 0 and 1 | from 0 to 1 | Not mandatory |
B2GPA IgM (U/mL) | Typical expect result is zero. Other parameters are abnormal | 0 and 1 | 0 and 1 | Not mandatory |
ACLA IgG (U/mL) | Typical expect result is zero. Other parameters are abnormal | 0 and 1 | 0 and 1 | Not mandatory |
ACLA IgM (U/mL) | Typical expect result is zero. Other parameters are abnormal | 0 and 1 | 0 and 1 | Not mandatory |
