Table 4 Association between each of the selected gene expressions with overall and disease-free survival.

From: A significant correlation exists between CREBBP and CEBPA gene expression in de Novo adult acute myeloid leukemia

Survival type

Gene expression

n (49)*

Proportion surviving at 6 months

Median survival estimate (months)

p-value

OS

CREBBP

Upregulated (9)

0.486

1.9

0.440

Downregulated (40)

0.898

18

CEBPA

Upregulated (12)

0.619

NR

0.595

Downregulated (37)

0.889

18

DNMT3A

Upregulated (11)

0.636

18

0.828

Downregulated (38)

0.919

18

DFS

CREBBP

Upregulated (9)

0.500

3

0.918

Downregulated (38)

0.571

6.5

CEBPA

Upregulated (12)

0.857

6.3

0.468

Downregulated (35)

1.00

6.1

DNMT3A

Upregulated (11)

0.714

9

0.147

Downregulated (36)

1.00

6

  1. (*) The number of patients who received the induction chemotherapy. Those were recategorized into 2 groups based on values of expression. The expression values above and below the 75th percentile were considered up and down-regulated, respectively.
Back to article page