Table 1 Baseline features of the study participants.

From: Identification and validation of biomarkers related to ferroptosis in idiopathic pulmonary fibrosis

 

Healthy controls (n = 60)

IPF (n = 95)

Statistics

P-value

Male, n (%)

29 (48.33)

46 (48.40)

χ2 = 0.000

0.992

Age (years)

69.72 ± 8.563

69.07 ± 7.669

t = 0.486

0.628

BMI (kg/m2)

22.92 (22.12, 23.41)

22.59 (20.24, 23.50)

z = 1.699

0.089

Smoking status

 Never smokers, n (%)

48 (80.0)

65 (68.4)

χ2 = 2.496

0.114

 Ex-smokers, n (%)

6 (10.0)

17 (17.9)

χ2 = 1.814

0.178

 Current mokers, n (%)

6 (10.0)

13 (13.7)

χ2 = 0.464

0.496

WBC (*10^9/L)

7.04 ± 2.13

7.30 ± 2.37

t = 0.680

0.497

CRP (mg/dL)

0.48 (0.35, 0.59)

0.43 (0.34, 0.54)

z = 1.566

0.117

PCT (ng/mL)

0.20 (0.11, 0.24)

0.17 (0.09, 0.24)

z = 0.636

0.525

ATM (pg/mL)

3012.62 (2226.87, 3568.81)

1182.88 (820.56, 1864.19)

z = 8.005

< 0.0001

FVC (% of predicted)

N/A

72.84 ± 9.49

  

DLCO (% of predicted)

N/A

49.13 ± 8.88

  

FEV1 (% of predicted)

NA

70.38 ± 10.71

  
  1. IPF idiopathic pulmonary fibrosis, BMI body mass index, WBC white blood cell, CRP C-reactive protein, PCT procalcitonin, ATM ataxia telangiectasia mutated, FVC forced vital capacity, DLCO diffusion capacity for carbon monoxide, FEV1 forced expiratory volume in one second.