Table 2 Univariate analyses of OS and RFS in patients with gastric cancer.
From: TMPRSS4 as a prognostic biomarker after gastric cancer surgery in a multicenter retrospective study
Variables | Number of patients | OS | p value | PFS | p value |
|---|---|---|---|---|---|
5-year survival rate (%) | 5-year survival rate (%) | ||||
Age | 0.247 | 0.092 | |||
70 < | 141 | 66.4 | 62.1 | ||
70 ≥ | 183 | 73.2 | 70.2 | ||
Gender | 0.0423 | 0.045 | |||
Male | 212 | 66.2 | 61.9 | ||
Female | 113 | 77.9 | 75.7 | ||
TMPRSS4 | 0.0149 | 0.0046 | |||
Positivity | 179 | 62.4 | 57.1 | ||
Negativity | 145 | 76.4 | 74.5 | ||
Tumor location | 0.2071 | 0.2732 | |||
Junction | 4 | 50.0 | 50.0 | ||
Upper | 59 | 70.6 | 61.0 | ||
Middle | 155 | 71.1 | 69.0 | ||
Lower | 106 | 70.2 | 67.4 | ||
Tumor size | 0.0029 | 0.0164 | |||
97 < | 263 | 53.1 | 52.1 | ||
97 ≥ | 61 | 74.3 | 70.1 | ||
Stage | < 0.0001 | < 0.0001 | |||
II | 128 | 89.8 | 84.8 | ||
III | 196 | 58.2 | 55.1 | ||
Depth of tumor invasion(T) | < 0.0001 | 0.0142 | |||
T1 | 14 | 85.7 | 78.6 | ||
T2 | 31 | 89.7 | 89.7 | ||
T3 | 137 | 77.8 | 71.0 | ||
T4 | 143 | 58.3 | 56.9 | ||
Lymph node metastasis (N) | < 0.0001 | < 0.0001 | |||
0 | 45 | 85.0 | 75.1 | ||
1 | 81 | 89.3 | 86.0 | ||
2 | 92 | 72.0 | 67.3 | ||
3 | 106 | 49.2 | 48.4 | ||
Lymphatic invasion (Ly) | 0.0014 | 0.0278 | |||
0 | 54 | 77.2 | 71.3 | ||
1 | 112 | 82.3 | 75.4 | ||
2 | 89 | 60.1 | 58.3 | ||
3 | 69 | 58.9 | 60.3 | ||
Venous invasion (v) | 0.7067 | 0.5548 | |||
0 | 117 | 70.2 | 67.5 | ||
1 | 114 | 72.2 | 65.6 | ||
2 | 68 | 63.9 | 62.2 | ||
3 | 25 | 80.0 | 80.0 | ||
Histology | 0.3084 | 0.4445 | |||
Differentiated | 120 | 72.3 | 68.8 | ||
Undifferentiated | 212 | 69.0 | 65.2 | ||
Tumor infiltrative type (IFN) | 0.0872 | 0.3692 | |||
a | 35 | 81.4 | 65.7 | ||
b | 136 | 73.4 | 70.7 | ||
c | 151 | 65.3 | 63.0 | ||
Lauren type | 0.1621 | 0.0904 | |||
i | 150 | 74.9 | 71.9 | ||
m | 42 | 70.7 | 58.0 | ||
d | 130 | 64.9 | 63.0 |
