Table 2 The binding affinity of the selected ligands from agarwood ethanol extract with their respective receptors.
Receptors | Selected ligands | Kcal/mol |
|---|---|---|
1PBT (Nogo-66 Receptor) | Positive ligand (α-D-GlcNAc) | − 6.43 |
Villinol | − 8.34 | |
Angustine | − 8.12 | |
Homaline | − 7.76 | |
7-Hydroxy-2' | − 7.96 | |
1WWB (TrkB receptor) | Positive ligand (1-N,3-N,5-N-tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide) | − 6.59 |
Tiliroside | − 8.62 | |
Villinol | − 8.16 | |
Homaline | − 7.80 | |
Angustine | − 7.54 | |
5HK1 (Sigma-1 receptor) | Positive ligand (Pentazocine) | − 7.91 |
Tiliroside | − 9.07 | |
Villinol | − 9.06 | |
Homaline | − 8.71 | |
7-Hydroxy-2' | − 8.51 | |
7CSQ (p75NTR) | Positive ligand ((2S,3S)-2-Amino-3-methyl-N-(2-morpholinoethyl) pentanamide) | − 6.28 |
7-Hydroxy-2' | − 8.31 | |
Homaline | − 8.21 | |
Villinol | − 7.50 |
