Fig. 6

Function of Macrophage-C1-C1QC_PPIF_high in LSCC tumor. (a, b) KEGG and GO analysis of deregulated expression gene of Macrophage-C1-C1QC_PPIF_high cells; (c) Volcano of differentially expressed genes in Macrophage-C1-C1QC_PPIF_high cells; (d, e) Circular plot displaying genes from three signaling pathways associated with tumor immunity, as identified in KEGG and GO analyses; (f–h) Diffusion pseudotime analysis in Macrophage-C1-C1QC_high cells of LSCC. (i–j) Comparison of CD163 expression and pro-tumor cytokine score between PPIF-high and PPIF-low Macrophage-C1-C1QC cells.