Fig. 2
From: Involvement of tdTomato-Tagged RPE cells in a mouse PVR model with enzymatically compromised retina
Establishment of a mouse model of PVR. A is a massaged eye. Arrow indicates bleeding. B is the sham control eye. C is a H&E histological image of a PVR-like retina with a typical funnel-shape morphology. The yellow arrow indicates a pigmented intraretinal membrane whereas the white arrow indicates a pigmented epiretinal membrane (ERM). Arrowheads: a retinal break. D is a sham control retina. E is a bar graph depicting the efficacies of PVR-like retinas induced by 0.6 U/mL dispase, massage, and combined treatments, and effect of 0.3 µM dasatinib treatment on reducing the PVR in two different mouse strains. *, p ≤ 0.05; ***, p ≤ 0.001.
