Fig. 5
From: Factor H-related 2 levels dictate FHR dimer composition
Genetic determinants in CFHR2 dictating dimer distribution. Impact of the common SNP rs4085749 and three low frequency SNPs: rs41310132, rs79351096 and rs41257905 on total levels of FHR-2 and FHR-1, -2 dimers in 77 healthy donors. (a) Schematic representation of the location and amino acid change of the SNPs within CFHR2. (b–e) Showing the impact of indicated SNPs on total FHR-2, FHR-1/1, -1/2 and -2/2 levels, respectively. (b–e) The Shapiro–Wilk test was used to test for normal distribution of the population. (b, c, d) The one-way ANOVA test or (e) the Kruskal Wallis test was used to test for significant differences. The (e) Dunn’s test or the (b, c, d) Tukey test were used to correct for multiple testing. Symbols represent the mean of two measurements with error bars indicating the median with interquartile range. (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).
