Fig. 7 | Scientific Reports

Fig. 7

From: In vivo deletion of a GWAS-identified Myb distal enhancer acts on Myb expression, globin switching, and clinical erythroid parameters in β-thalassemia

Fig. 7

Adult and fetal globin genes expression in Myb − 81kb enhKO animals. (a) E13.5 fetal liver cells were sorted into four populations based on the CD71 and Ter119 surface markers. Sorted cells were used to perform qRT-PCR analyses of (b) Myb, (c) embryonic globins Hbb-bh1, Hbb-y, (D) adult β-globin Hbb-b1, Hbb-b2, and (E) adult α-globin Hba-a1 genes expression. All data are expressed as the mean ± s.e.m. *P < 0.05, **P < 0.01, ***P < 0.001.

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