Fig. 8
From: Centrobin serves as a safeguard to guide timely centriole maturation during the cell cycle
Analysis of centrobin KO mice (a) Centrobin KO MEF lines were coimmunostained with centrin2 (green) and Cep164 (red) antibodies. (b) The number of centriolar Cep164 signals per cell was counted. (c) Centrobin KO MEF lines were coimmunostained with Arl13b (green) and centrin2 (red) antibodies. (d) The number of cells with cilia was counted. (e, f) The sizes of testes from the wild-type and centrobin KO mice were measured. At least three mice per group were used. (g–j) Testes and epididymis of the wild type and centrobin KO mice were subjected to H&E staining analyses. Scale bars, 100 μm. (a, c) Scale bars, 10 μm. (b, d) More than 90 cells per group were counted in 3 independent experiments. Statistical significance was determined using paired t-test. *, P < 0.05; **, P < 0.01.
