Fig. 2
C3G ameliorated UUO-induced epithelial-mesenchymal transition and extracellular matrix deposition. (A-B) E-cadherin, Snail, vimentin and N-cadherin protein level were examined in different groups, and the quantification of snail, vimentin and N-cadherin protein level relative to the sham-operated group. (C) mRNA levels of E-cadherin, snail, vimentin and N-cadherin were detected by real-time RT-PCR in different treatment groups. (D-E) FN, collagen I and collagen III protein level were examined in different groups, and the quantification of FN, collagen I and collagen III protein level relative to the sham-operated group. (F) mRNA levels of FN, collagen I and collagen III were detected by real-time RT-PCR in different treatment groups. Values were expressed as the mean ± SEM. *P < 0.05, relative to the sham group. #P < 0.05, relative to the UUO group.
