Fig. 6 | Scientific Reports

Fig. 6

From: Cyanidin-3-glucoside upregulated NDRG2 through the PI3K/AKT pathway to alleviate EMT and ECM in renal fibrosis

Fig. 6

C3G reversed NDRG2 reduction induced by UUO and TGF-β1 treatment. (A-C) NDRG2 protein and mRNA level were detected to investigate the effect of C3G on TGF-β1 induced HK-2 cells, and the quantification was showed as relative to control group. (D) Immunofluorescence was performed to see the localization of NDRG2. (E-G) NDRG2 protein and mRNA level were detected to demonstrate the effect of C3G on UUO mice, and the quantification was showed as relative to sham-operated group. Values were expressed as the mean ± SEM. *P < 0.05, relative to the sham and control group. #P < 0.05, relative to the UUO and TGF-β1 group.

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