Fig. 7
C3G regulated EMT and extracellular matrix deposition induced by TGF-β1 on HK-2 cell through NDRG2. (A-C) NDRG2 protein level was detected by western blot and real-time PCR after si-NDRG2 transfection. (D) E-cadherin, Snail, vimentin and N-cadherin protein level were examined in different groups, and the quantification was shown as relative to the control group. (E) FN, Col-I and Col-III protein level were examined in different groups, and the quantification was shown as relative to the control group. Values were expressed as the mean ± SEM. *P < 0.05, relative to the control group. #P < 0.05, relative to the TGF-β1 + C3G group.
