Fig. 7
Analysis and validation of core target genes involved in mediating cardiac repair. (A) Expression levels of the CDC6 gene in normal human fetal tissues, as obtained from NCBI. (B) Expression levels of the CDC6 gene in normal adult human tissues, as sourced from NCBI. (C) Establishment of in vivo mouse myocardial infarction animal models and ex vivo primary neonatal cardiomyocyte OGD models. (D) Animal models were utilized to verify the expression levels of the CDC6 gene at various time points following myocardial infarction. (E) Cellular models confirmed the expression levels of the CDC6 gene under different durations of hypoxia. (F) Validation of genes mediating cardiac repair (Cnpy2, Mfge8, Gdfl5, Atf4, Mrps5, and Cpt1b).
