Table 2 The values of functional scale scores for all patients and by Nusinersen and Risdiplam group.
From: Functional and structural analysis of SITTER patients with spinal muscular atrophy
Parameter | All SMA sitter (n = 21) | Nusinersen (n = 9) | Risdiplam (n = 12) | |||
|---|---|---|---|---|---|---|
HFMSE | RULM | HFMSE | RULM | HFMSE | RULM | |
Initial examination (0-month) | ||||||
Median | 23 | 30 | 32 | 30 | 22 | 31 |
Min–max | 5–45 | 14–43 | 5–42 | 14–41 | 8–45 | 24–43 |
Q25–Q75 | 14–35 | 27–36 | 14–35 | 27–37 | 15–32 | 28–35 |
Follow-up examination (12-month) | ||||||
Median | 23 | 32 | 34 | 34 | 23 | 32 |
Min–max | 6–46 | 17–43 | 6–43 | 17–42 | 9–46 | 24–43 |
Q25–Q75 | 14–36 | 29–37 | 14–36 | 30–37 | 14–34 | 28–36 |
The difference between examinations | ||||||
Wilcoxon test | z = 0.62 | z = 2.34 | z = 1.33 | z = 2.31 | z = 0.16 | z = 1.02 |
p = 0.538 | p = 0.02 | p = 0.183 | p = 0.02 | p = 0.875 | p = 0.308 | |
