Fig. 3

Mutational characteristics between two molecular subtypes. A Difference analysis of TMB score among two subtypes. B Somatic mutation analysis of the top 15 highly mutated genes of C1 subtype. C Somatic mutation analysis of the top 15 highly mutated genes of C2 subtype. D Mutation frequency of C1 subtype tumor pathway gene and proportion of affected samples. E Mutation frequency of C2 subtype tumor pathway genes and proportion of affected samples.