Table 1 CD3+ and TCRγδ + cell counts in CE cysts and tissue controls with/without Fasciola hepatica co-infection.

From: γδ T cell distribution in the adventitial layer of non-fertile cystic echinococcosis cysts from cattle livers

Study group

n

Area

CD3+ cells/mm2 count

TCRγδ + cells/mm2 count

TCRγδ+/CD3+ percentage (%)

Mean ± SD

P-value

Mean ± SD

P-value

Mean ± SD

P-value

CE + FH-

4

AL-Inf

2,323 ± 727

0.0264*

620 ± 298

0.1478

26.1 ± 7.4

0.8278

AL-Fib

1,088 ± 428

315 ± 21

27.4 ± 9.3

CE + FH+

4

AL-Inf

2,154 ± 631

0.0048*

314 ± 95

0.052

15.4 ± 5.8%

0.5047

AL-Fib

646 ± 284

135 ± 113

18.7 ± 7%

CTRL

5

AL-Inf

340 ± 188

0.0168*

12 ± 8

0.0019*

3.7 ± 2.7%

0.1032

AL-Fib

800 ± 258

51 ± 18

6.6 ± 2.1%

FH+

5

AL-Inf

187 ± 72

0.0165

11 ± 7

0.0513

6 ± 3.2

0.0479*

AL-Fib

663 ± 345

79 ± 67

11.4 ± 4.1

  1. Data represents mean ± Standard deviation (SD) of cell counts per mm2 or percentage of TCRγδ + in CD3+ population. Percentages and counts derived from the count of positive cells from 6 ROIs per sample, each with an area of 37,539 μm2. Statistical significance assessed with student t-test (p-value < 0.05); *p < 0.05. CE+. CE + FH-: non-fertile CE cysts non-co-infected with Fasciola hepatica; CE + FH+: non-fertile CE cysts co-infected with Fasciola hepatica, AL: Adventitial Layer, Inf: Inflammatory infiltrate, Fib: fibrosis, CTRL: control tissue for non-infected animal, FH+: Fasciola hepatica tissue control, LI: Liver, Par: Parenchyma, PA: Portal area.
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