Fig. 2 | Scientific Reports

Fig. 2

From: Protective effects of baicalin against deoxynivalenol-induced oxidative and inflammatory damage in chicken-derived hepatic 3D cell cultures

Fig. 2

Effects of (a) 24 h and (b) 48 h of deoxynivalenol (DON) and baicalin (BAI) treatment on the metabolic activity of primary hepatic 3D cell co-cultures of chicken origin assessed by CCK-8 test. BAI and DON-treated cells were compared to the control group. Different baicalin and 2 µg/mL DON-treated cells were compared to the 2 µg/mL DON group. Different baicalin and 20 µg/mL-DON treated cells were compared to the 20 µg/mL DON group. The metabolic activity of the cells was overall increased by the baicalin treatment after 24 and 48 h, and decreased by the applied DON concentrations after 24 h. Control: cells without DON or BAI exposure; BAI: cells treated with BAI; DON: cells treated with DON; DON + BAI: cells treated with the combination of DON and BAI. See Table 1 for detailed concentrations. Results are expressed as mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001.

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