Fig. 4

At satiety, social reward-seeking behavior is unaffected by juvenile social isolation. (A) Mean total time spent investigating a social stimulus or a chamber containing food following jSI at P21-P42 and subsequent re-housing until P60 (jSI-A). Male GH, n = 15; male jSI-A, n = 15; female GH, n = 18; female jSI-A, n = 16. (B) Mean total investigation time for the social stimulus and a chamber containing food plotted in 1-min intervals over the 5-min testing period. C. Mean bout duration representing the average length of time spent investigating the social stimulus or the chamber containing food. (D-F) Data for social reward-seeking behavior observed immediately after jSI at P21-P42, without to re-housing (jSI-B), using the same analysis as in A-C. Male GH, n = 12; male jSI-B, n = 16; female GH, n = 12; female jSI-B, n = 8. Statistical significance indicated as ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05 based on post-hoc tests following the main effect. Error bars represent standard error of the mean (SEM).