Table 3 Comparison of diagnostic performance of CT attenuation-based parameters for assessing hepatic steatosis between patients with and without severe fibrosis.

Hepatic steatosis grades	CT parameters	AUROC (95% CI)		P-value^*
Hepatic steatosis grades	CT parameters	Patients with severe fibrosis (n = 70)	Patients without severe fibrosis (n = 173)	P-value^*
Mild	L_pre	0.645 (0.521–0.756)	0.698 (0.623–0.765)	0.56
	L-S_pre	0.568 (0.444–0.686)	0.634 (0.557–0.706)	0.48
	L_post	0.623 (0.499–0.736)	0.694 (0.620–0.762)	0.40
	L-S_post	0.516 (0.394–0.638)	0.642 (0.566–0.713)	0.15
Moderate	L_pre	0.676 (0.554–0.783)	0.804 (0.737–0.861)	0.22
	L-S_pre	0.616 (0.492–0.730)	0.707 (0.633–0.773)	0.43
	L_post	0.621 (0.497–0.734)	0.744 (0.673–0.808)	0.19
	L-S_post	0.564 (0.440–0.682)	0.706 (0.633–0.773)	0.15
Severe	L_pre	0.659 (0.536–0.769)	0.843 (0.781–0.894)	0.13
	L-S_pre	0.687 (0.565–0.793)	0.742 (0.670–0.806)	0.66
	L_post	0.706 (0.585–0.809)	0.755 (0.684–0.817)	0.58
	L-S_post	0.525 (0.402–0.646)	0.765 (0.695–0.826)	0.037

Note. – AUROC, area under the receiver operating characteristic curve; CI, confidence interval; L_pre and L_post refer to the mean liver HU on pre- and post-contrast CT images, respectively; L-S_pre and L-S_post refer to the difference in mean HU between the liver and spleen on pre- and post-contrast CT images, respectively. ^*Calculated using z-statistics.

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