Fig. 2

PCO heterogeneity in growth. (a) Representative PCO brightfield microscopy (patient MC1, see Supp. Table 2) annotated with percent difference in individual organoid diameter. (b) Baseline clinical characteristics for cultures colored by the key below, including pathologic review of tumor grade and clinical parameters of stage from tumor (T), node (N) and metastases (M) combined to complete diagnostic staging (Stage). Current disease status noted (Recurrence in black). (c) Dot plots colored by the key below for primary tumor type (Primary) for localized rectal (light green), metastatic rectal (dark green), localized colon (light blue), metastatic colon (dark blue), breast (purple), ovarian (beige), gastrointestinal stromal tumor (GIST, gray), and lung (white) with each point representing an individual organoid for normalized Δ diameter at 48 h, median denoted with vertical bar (orange).