Table 2 Results of Healthy Participants versus LTLE group for two-way repeated-measures MANOVA for recruitment and flexibility within subcortical and cortical subsystems for the four subcortical/cortical subsystem combinations(thalamus, striatum, mesial-temporal and cerebellar subsystems with all cortical subsystems).

From: Multiple subcortical and subcortico–cortico dynamic network reconfigurations characterize focal-to-bilateral tonic–clonic seizures

Source	df or Hypothesis df/error df	F	Sig	Partial Eta Squared	Observed power	Source	df or hypothesis df/error df	F	Sig	Partial eta Squared	Observed power
Recruitment						Flexibility
Among thalamus and cortical subsystems
WS Hemisphere	1	2.028	0.157	0.018	0.292	^bWS Hemisphere	1	4.461	0.037	0.039	0.553
WS Hemisphere X Group	1	0.485	0.488	0.004	0.106	WS Hemisphere X Group	1	0.407	0.525	0.004	0.097
WS Subsystems X Group	5.411	0.460	0.820	0.004	0.181	WS Subsystems X Group	5.404	0.673	0.666	0.006	0.255
^aWS Hemisphere X Subsystem	4.857	4.843	0.000	0.043	0.978	^cWS Hemisphere X Subsystem	7.080	2.505	0.015	0.022	0.885
WS Hemisphere X Subsystem X Group	4.857	0.516	0.759	0.005	0.190	WS Hemisphere X Subsystem X Group	7.080	0.585	0.770	0.005	0.257
BTWS Group	1/109	1.368	0.245	0.012	0.213	BTWS Group	1/109	1.192	0.277	0.011	0.191
Among striatum and cortical subsystems
^dWS Hemisphere	1	4.170	0.044	0.037	0.526	WS Hemisphere	1	0.118	0.732	0.001	0.063
WS Hemisphere X Group	1	2.418	0.123	0.022	0.338	WS Hemisphere X Group	1	0.281	0.597	0.003	0.082
WS Subsystems X Group	6.950	1.093	0.366	0.010	0.474	WS Subsystems X Group	7.749	0.357	0.939	0.003	0.171
^eWS Hemisphere X Subsystem	5.009	2.317	0.042	0.021	0.747	^fWS Hemisphere X Subsystem	8.212	1.896	0.056	0.017	0.809
WS Hemisphere X Subsystem X Group	5.009	1.540	0.176	0.014	0.541	WS Hemisphere X Subsystem X Group	8.212	0.647	0.742	0.006	0.309
BTWS Group	1/109	1.307	0.255	0.012	0.205	BTWS Group	1/109	0.194	0.660	0.002	0.072
Among mesial temporal and cortical subsystems
^gWS Hemisphere	1	4.818	0.030	0.042	0.585	WS Hemisphere	1	0.448	0.505	0.004	0.102
WS Hemisphere X Group	1	0.309	0.579	0.003	0.085	WS Hemisphere X Group	1	0.7.9	0.402	0.006	0.133
WS Subsystems X Group	4.895	0.853	0.510	0.008	0.304	WS Subsystems X Group	5.724	0.606	0.718	0.006	0.238
WS Hemisphere X Subsystem	3.744	1.941	0.107	0.017	0.564	WS Hemisphere X Subsystem	6.347	1.530	0.161	0.014	0.613
WS Hemisphere X Subsystem X Group	3.744	0.829	0.501	0.008	0.256	WS Hemisphere X Subsystem X Group	6.347	1.055	0.389	0.010	0.435
BTWS Group	1/109	2.082	0.152	0.019	0.299	BTWS Group	1/109	0.065	0.799	0.001	0.057
Among cerebellar/cortical subsystems
WS Hemisphere	No recruitment for Cerebellar subsystems					WS Hemisphere	1	0.032	0.858	0.000	0.054
WS Hemisphere X Group						WS Hemisphere X Group	1	1.134	0.289	0.010	0.184
WS Subsystems X Group						WS Subsystems X Group	7.903	1.120	0.347	0.010	0.523
WS Hemisphere X Subsystem						^hWS Hemisphere X Subsystem	7.957	2.003	0.044	0.018	0.824
WS Hemisphere X Subsystem X Group						ⁱWS Hemisphere X Subsystem X Group	7.957	2.142	0.030	0.019	0.854
BTWS Group						BTWS Group	1/109	0.006	0.938	0.000	0.051

The univariate test results showing main effects and interactions of condition, experimental group, and subsystems for recruitment and flexibility. Pairwise comparisons were also tested for the results showing a significant univariate effect to determine the nature of the differences between those variables (See suppl. section). WS—Within-subject effect, BTWS—Between-subject effect. Significant effects are highlighted in bold.
*Multivariate effect is significant at p < 0.05 or less.

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