Fig. 1 | Scientific Reports

Fig. 1

From: A novel peptide RR-171 derived from human umbilical cord serum induces apoptosis and pyroptosis in pancreatic cancer cells

Fig. 1

RR-171 suppresses pancreatic cancer cell viability and proliferation in vitro. (A) Capan-2, Bxpc-3, and Panc-1 cell viability was determined using a CCK-8 analysis after treatment with different concentrations of RR-171. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the 0 µM RR-171 treatment group. (B) Colony formation assay to identify the effect of RR-171 on pancreatic cancer cell proliferation. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the 0 µM RR-171 treatment group. (C) The proliferation of Capan-2 and Bxpc-3 cells was determined using an EdU assay after treatment with increasing concentrations of RR-171. The nuclei were stained with Hoechst (blue), and the proliferating cells were stained with EdU (green) (200×).

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