Table 2 Efficacy of poly-sialylated glycan candidates in predicting preterm birth.

From: Poly-sialylated glycan of cervicovaginal fluid can be a potential marker of preterm birth

N-glycopeptides (C/H-S glycan)

AUC

P-value

SENS

SPEC

PPV

NPV

Accuracy

CTTNBP2 NL

EENRTK + HexNAc(5)Hex(6)NeuAc(3)

0.843

0.008

75%

87.5%

90%

70%

80%

ORM2

NEEYNK + HexNAc(5)Hex(6)NeuAc(3)

0.802

0.007

75%

87.5%

90%

70%

80%

SERPINA1

YLGNATAIFFLPDEGK + HexNAc(4)Hex(5)NeuAc(2)

0.875

0.002

75%

87.5%

90%

70%

80%

  1. AUC; area under the curve, SENS; sensitivity, SPEC; specificity, PPV; positive predictive value, NPV; negative predictive value.
  2. CTTNBP2 NL; CTTNBP2 N-terminal like, ORM2; Orosomucoid, Alpha- 1-acid glycoprotein 2, SERPINA1; serine protease inhibitor alpha- 1 antitrypsin.