Table 1 Clinical characteristics of patients with intracranial infection or non-infection after neurosurgery at admission.

From: Combination value of cell index, CSF PCT, and CSF IL-6 for intracranial infection diagnosis after neurosurgery

 

Intracranial infection group (n = 48)

Intracranial non-infection group (n = 154)

P value

Male (%)

26 (54.17)

80 (51.95)

0.788

Age (years)

50.67 ± 15.53

50.61 ± 14.33

0.981

BMI (kg/m2)

22.92 ± 2.4

22.62 ± 2.23

0.435

Comorbidities (%)

22 (45.83)

75 (48.70)

0.728

Hypertension (%)

17 (35.42)

58 (37.66)

0.779

Diabetes (%)

5 (10.42)

14 (9.09)

0.784

CVA (%)

2 (4.17)

4 (2.60)

0.576

CHF (%)

2 (4.17)

6 (3.90)

0.933

COPD (%)

2 (4.17)

5 (3.25)

0.761

CRI (%)

3 (6.25)

6 (3.90)

0.490

APACH-II score

16.94 ± 3.55

16.58 ± 3.26

0.514

SOFA score

6.40 ± 1.33

6.10 ± 1.23

0.161

GCS

6.04 ± 2.31

6.14 ± 2.23

0.785

Numbers of surgery

1.29 ± 0.54

1.2 ± 0.42

0.227

Cumulative operation time (hours)

4.24 ± 1.96

3.17 ± 1.16

0.000

Preventive use of antibiotics (n, %)

45 (93.75)

147 (95.45)

0.635

Number of drainage tubes

1.94 ± 0.81

1.73 ± 0.72

0.099

Drainage tube placement time (days)

5.79 ± 1.95

4.63 ± 1.52

0.000

Intrathecal injection of drugs

7 (14.58)

18 (11.69)

0.595

Time from postoperation

to suspected infection (days)

6.63 ± 2.73

4.72 ± 1.82

0.000

  1. CVA: cerebrovascular accident; CHF: chronic heart failure; COPD: chronic obstructive pulmonary disease; CRI: chronic renal insufficiency; APACHE-II: acute physiology and chronic health evaluation II score; SOFA: sepsis related organ failure assessment; GCS: Glasgow coma scale.