Fig. 1 | Scientific Reports

Fig. 1

From: Transcriptional regulation of ETV5 by mitogen-activated protein kinase via ETS-1 in human pancreatic cancer cells

Fig. 1

Alterations of ETV5 expression by ERK1/2 inhibition. (A) qRT-PCR of human pancreatic cancer cells treated with U0126 (U) or dimethyl sulfoxide (D). (B) A representative immunoblot of human pancreatic cancer cells treated with (+) or without (-) U0126 probed for the expression of phosphorylated ERK (pERK), ERK, ETV5, and β-actin. Original blots are shown in Supplemental Figure S1. (C and D) Densitometry analyses of the expression of pERK (C) and ETV5 (D) relative to that of β-actin in immunoblots of pancreatic cancer cells treated with U0126 (U) or dimethyl sulfoxide (D ). Asterisks indicate that *, p < 0.05; and **, p < 0.01. Graphs show means and standard errors of duplicate experiments.

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