Fig. 1

In vitro cytotoxicity assay analysis of U87-MG cells for 72 h. (A) The effect of siRNAs only against U87-MG cell viability. (B) The effect of serial does of doxorubicin (DOX) alone or in combination with 100 nM of siRNAs. (C) The effect of serial does of temozolomide (TMZ) alone or in combination with 100 nM of siRNAs. (D) The effect of serial doses of doxorubicin (DOX) alone or in combination with both siRNAs (siPFKFB4 and siHMOX1). (E) The effect of serial doses of temozolomide (TMZ) alone or in combination with both siRNAs (siPFKFB4 and siHMOX1).