Table 2 Clinical characteristics of PMN with and without thromboembolism events during study follow up.
From: Nomogram for thromboembolic events in primary membranous nephropathy associated with PLA2R antibody
Variables | With thromboembolism(N = 126) | without thromboembolism(N = 843) | P-valve |
---|---|---|---|
Gender (male/ female) | 93/ 33 | 547/ 296 | 0.049* |
Age (year) | 57 (49, 64) | 51 (42, 59) | < 0.001* |
PLA2R-antibody titer (RU/ml) | 102.8 (43.7, 363.3) | 54.4 (15.8, 136.2) | < 0.001* |
Creatinine (µmol/L) | 78 (65, 103) | 71 (59, 85) | < 0.001* |
24-h proteinuria (g) | 6.29 (3.53, 9.75) | 4.75 (2.58, 7.44) | 0.001* |
Albumin (g/L) | 22.3 (17.7, 26.1) | 24.1 (20.2, 28.9) | < 0.001* |
haemoglobin (g/L) | 125 (112, 137) | 132 (119, 144) | < 0.001* |
Platelet (×109/L) | 238 (195, 280) | 237 (193, 281) | 0.796 |
Total cholesterol (mmol/l) | 6.91 (5.61, 8.78) | 7.06 (5.65, 8.69) | 0.904 |
Low-density lipoprotein (mmol/l) | 4.53 (3.195, 6.28) | 4.76 (3.48, 6.25) | 0.385 |
D-Dimer (g/ml) | 0.60 (0.23, 2.05) | 0.29 (0.15, 0.66) | < 0.001* |
Fibrinogen (mg/dl) | 4.3 (3.7, 5.1) | 4.1 (3.5, 4.7) | 0.006* |
APTT | 30.5 (27.4, 34.4) | 30 (27.4, 32.6) | 0.051 |
PT | 9.9 (9.3, 10.6) | 9.7 (9.3, 10.2) | 0.027* |