Table 2 Clinical characteristics of PMN with and without thromboembolism events during study follow up.

From: Nomogram for thromboembolic events in primary membranous nephropathy associated with PLA2R antibody

Variables

With thromboembolism(N = 126)

without thromboembolism(N = 843)

P-valve

Gender (male/ female)

93/ 33

547/ 296

0.049*

Age (year)

57 (49, 64)

51 (42, 59)

< 0.001*

PLA2R-antibody titer (RU/ml)

102.8 (43.7, 363.3)

54.4 (15.8, 136.2)

< 0.001*

Creatinine (µmol/L)

78 (65, 103)

71 (59, 85)

< 0.001*

24-h proteinuria (g)

6.29 (3.53, 9.75)

4.75 (2.58, 7.44)

0.001*

Albumin (g/L)

22.3 (17.7, 26.1)

24.1 (20.2, 28.9)

< 0.001*

haemoglobin (g/L)

125 (112, 137)

132 (119, 144)

< 0.001*

Platelet (×109/L)

238 (195, 280)

237 (193, 281)

0.796

Total cholesterol (mmol/l)

6.91 (5.61, 8.78)

7.06 (5.65, 8.69)

0.904

Low-density lipoprotein (mmol/l)

4.53 (3.195, 6.28)

4.76 (3.48, 6.25)

0.385

D-Dimer (g/ml)

0.60 (0.23, 2.05)

0.29 (0.15, 0.66)

< 0.001*

Fibrinogen (mg/dl)

4.3 (3.7, 5.1)

4.1 (3.5, 4.7)

0.006*

APTT

30.5 (27.4, 34.4)

30 (27.4, 32.6)

0.051

PT

9.9 (9.3, 10.6)

9.7 (9.3, 10.2)

0.027*

  1. Data presented as median (first-third interquartile range) or mean ± SD or number (percentage). MN, membranous nephropathy; PLA2R antibody, phospholipase A2 receptor antibody; APTT, Activated partial thromboplastin time; PT, Prothrombin time.