Table 4 Multivariate logistic regression analysis between selected parameters and thromboembolism events in patients with anti-PLA2R-positive PMN (Forward, LR, α = 0.05).

From: Nomogram for thromboembolic events in primary membranous nephropathy associated with PLA2R antibody

Variable

Partial regression coefficient

Standard error

Wald χ2

OR(95%CI)

P-valve

Age (year)

0.034

0.009

3.856

1.03 (1.02, 1.05)

< 0.001*

Gender (female/ male)

-0.300

0.254

-1.183

0.74 (0.45, 1.22)

0.237

PLA2R-Ab titer ≤ 36.9RU/ml/

PLA2R-Ab titer > 36.9RU/ml

1.012

0.255

3.961

2.75 (1.67, 4.54)

< 0.001*

24-h proteinuria (g)

0.050

0.023

2.218

1.05 (1.01, 1.10)

0.027*

Albumin (g/L)

0.000

0.022

0.021

1.00 (0.96, 1.05)

0.983

Creatinine (µmol/L)

-0.000

0.002

-0.230

1 (1, 1)

0.818

Haemoglobin (g/L)

-0.004

0.007

-0.669

1.00 (0.98, 1.01)

0.503

D-Dimer (g/ml)

0.273

0.059

4.614

1.31 (1.17, 1.48)

< 0.001*

Fibrinogen (mg/dl)

0.106

0.091

1.168

1.11 (0.93, 1.33)

0.243

  1. *Stands for p < 0.05. MN, membranous nephropathy; PLA2R-Ab, phospholipase A2 receptor antibody.