Fig. 3 | Scientific Reports

Fig. 3

From: CMPK2 promotes microglial activation through the cGAS-STING pathway in the neuroinflammatory mechanism

Fig. 3

LPS Enhances microglial-mediated neuroinflammation via the cGAS/STING Pathway. (A) Western blot analysis of cGAS and STING protein levels under different treatments. (B) Analysis of cGAS and STING mRNA expression under different treatments. (C) Flow cytometry analysis of oxidative stress (ROS) levels under different treatments.D,E. Analysis of mRNA and protein expression levels of IL-6, TNF-α, IL-1β, and TGF-β. The presented data represent the mean ± standard deviation (SD) derived from three independent experiments. Statistical significance of the fold change was determined, with *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001 denoting the significance levels.

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