Table 3 Threshold Effect Analysis of serum uric acid levels and testosterone levels using two-piecewise Linear Regression.

From: Potential links between serum uric acid levels and testosterone levels in adult males: a cross-sectional study

Models

Effect size (β)

95% CI

P value

Serum uric acid (mg/dL)

 Model 1

   

  One line effect

− 12.31

− 15.69 to − 8.94

 < 0.0001

 Model 2

   

  Inflection point

   

  < 4.4

17.93

− 3.61 to 39.48

0.1028

  ≥ 4.4

− 14.73

− 18.51 to − 10.95

 < 0.0001

 P value for LRT test*

  

0.005

  1. Model 1, linear analysis; Model 2, non− linear analysis.
  2. Adjusted: age, race, BMI, ALT, AST, hypertension, diabetes, hyperlipidemia, ASCVD, CKD, smoking status and drinking status. CI, confidence interval; LRT, logarithm likelihood radio test; BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ASCVD, Atherosclerotic Cardiovascular Disease; CKD, Chronic kidney disease.
  3. *P < 0.05 indicates Model 2 is significantly different from Model 1.
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