Fig. 3
HCC Overall Survival based on HLA-G extended haplotypes. The overall survival (OS) of HCC-specific mortality is graphically presented for a cohort of 116 patients observed over a 60-months time frame. Patients were categorized based on their HLA-G extended haplotypes (HLA-G alleles with 3’UTR) in HLA-G*01:01:01/UTR-1 homozygous, HLA-G*01:01:01/UTR-1 heterozygous or HLA-G other extended haplotypes (HLA-G alleles with their UTR). P-values were calculated using the two-sided log-rank test. A) Overall Survival based on HLA-G extended haplotypes in patients with HCC related to HCV and/or HBV infection. The overall survival (OS) of HCC-specific mortality is graphically presented for a cohort of 95 patients observed over a 60-months time frame. Patients were categorized based on their HLA-G extended haplotypes (HLA-G alleles with 3’UTR) in HLA-G*01:01:01/UTR-1 homozygous, HLA-G*01:01:01/UTR-1 heterozygous or HLA-G other extended haplotypes (HLA-G alleles with their UTR). P-values were calculated using the two-sided log-rank test. B) Overall Survival based on HLA-G extended haplotypes in patients with HCC SLD related. The overall survival (OS) of HCC-specific mortality is graphically presented for a cohort of 21 patients observed over a 60-months time frame. Patients were categorized based on their HLA-G extended haplotypes (HLA-G alleles with 3’UTR) in HLA-G*01:01:01/UTR-1 homozygous, HLA-G*01:01:01/UTR-1 heterozygous or HLA-G other extended haplotypes (HLA-G alleles with their UTR). P-values were calculated using the two-sided log-rank test. This HCC patients subgroup included ALD and MASLD/MASH. Abbreviations: SLD = Steatotic liver disease; ALD = Alcoholic liver disease; MASLD = Metabolic dysfunction associated with steatotic liver disease; MASH = Metabolic dysfunction associated with steatohepatitis.
