Fig. 6 | Scientific Reports

Fig. 6

From: Accre 8 emerging point of care CLIA system for vitamin B12 assessment compared with three established assays

Fig. 6

ROC curve analysis for Accre, Roche, LC-MS/MS, and Abbott. Graphs [A–C] illustrate the diagnostic performance of Accre, Abbott, and Roche assays in comparison to LC-MS/MS for Vitamin B12 quantification. Panel A presents the ROC curve for Accre 8 vs. LC-MS/MS, yielding an AUC of 0.98 (P < 0.001). Panel B shows the ROC curve for Abbott vs. LC-MS/MS, also with an AUC of 0.98 (P < 0.001). Panel C displays the ROC curve for Roche vs. LC-MS/MS, which exhibited the highest AUC of 0.99 (P < 0.001), indicating the closest agreement with the reference method. AUC values between 0.9 and 1.0 are considered excellent, demonstrating high diagnostic accuracy across all assays.

Back to article page