Table 1 Demographic background of the sample, stratified by Strong profile.
HC | ALSni | ALSbi | ALSci | ALS-FTD | |
|---|---|---|---|---|---|
N | 32 | 45 | 11 | 23 | 5 |
Age at onset | – | 56.32 (9.76) | 54.78 (13.74) | 59.94 (11.15) | 54.95 (10.93) |
chronological age | 61.07 (11.19) | 59.20 (9.38) | 57.90 (12.47) | 63.34 (9.50) | 56.59 (10.71) |
brain age | 58.86 (12.51) | 55.69 (9.91) | 56.80 (14.20) | 66.67 (11.51) | 62.56 (7.70) |
PAD | -2.20 (5.72) | -3.54 (5.46) | -1.10 (3.64) | 3.33 (5.95) | 5.97 (10.64) |
educational years | 13.16 (1.69) | 13.49 (2.75) | 14.00 (2.00) | 11.87 (1.71) | 13.40 (1.67) |
Premorbid IQ | 104.41 (8.38) | 103.00 (11.79) | 102.91 (8.58) | 93.57 (9.58) | 96.00 (6.89) |
Cognitive reserve | 40.79 (3.00) | 40.43 (4.89) | 40.61 (3.33) | 36.65 (3.36) | 38.07 (2.64) |
ALS-FRS-R | – | 39.38 (6.30) | 36.09 (7.53) | 39.91 (5.08) | 43.20 (2.77) |
ALS-FRS-R delta | – | 0.53 (0.40) | 0.89 (0.92) | 0.56 (0.36) | 0.39 (0.21) |
Disease Duration (months) | – | 34.20 (23.94) | 16.75 (12.90) | 23.11 (13.28) | 23.00 (19.09) |
Sex (f/m) | 27/18 | 7/4 | 16/7 | 4/1 | |
Phenotype (PLS, PMA, UMN, classic, flail arm, flail leg, uncertain) | – | 5/4/3/24/4/3/2 | 0/1/0/10/0/0/0 | 1/2/2/15/2/1/0 | 0/0/3/2/0/0/0 |
Onset Type (bulbar, limb, uncertain) | – | 27/12/6 | 5/4/2 | 11/8/4 | 1/4/0 |
