Fig. 4 | Scientific Reports

Fig. 4

From: Machine learning-based integration reveals reliable biomarkers and potential mechanisms of NASH progression to fibrosis

Fig. 4

Characterization of key genes in NASH fibrosis in diagnostic models. (A) The volcano plot illustrates the differential expression and statistical significance of key genes in the diagnostic model related to NASH fibrosis. (B) The box plot displays the relative expression levels of key genes in various diagnostic models for NASH fibrosis. (C) The ROC curves demonstrate the diagnostic efficacy of different key genes in the diagnostic models for NASH fibrosis. (D) The Pearson correlation analysis reveals the relationships between key genes in the diagnostic model, assessing their synergistic or antagonistic interactions. (E) Based on GeneMANIA (http://genemania.org/), this analysis explores the interactions and functional predictions of key genes in the diagnostic model. All images were created using R software (version 4.3.1, https://www.r-project.org).

Back to article page