Fig. 3 | Scientific Reports

Fig. 3

From: A three-subtype prognostic classification based on base excision repair and oxidative stress genes in lung adenocarcinoma and its relationship with tumor microenvironment

Fig. 3

Different gene expression character analysis of the three subtypes in TCGA database. (A) KEGG enrichment analysis of DEGs among the three subtypes. (B) GO enrichment analysis of DEGs among the three subtypes in biological process, cellular component and molecular function. (C) Protein–protein interaction network analysis using all 271 DEGs. The color represents the number of interactive proteins. From yellow to red, the darker the color, the greater the number of interacting proteins. (D) Seven central DEGs among the three subtypes with the strongest interaction. The color represents the number of interactive proteins. From yellow to red, the darker the color, the greater the number of interacting proteins. (E) The expression of the seven central DEGs in C1, C2 and C3, respectively. The T test was used to determine differences between tumor and normal tissues. A p value of < 0.05 /<0.01/<0.001/ <0.0001 denoted by an asterisk */**/***/**** in figures.

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