Table 2 Comparison of indicators among different CKD groups.

From: 25(OH)D3 and F-25(OH)D as indicators of chronic kidney disease progression in patients with rheumatoid arthritis

Item

Mild CKD group (n = 1237)

Moderate CKD group (n = 182)

Severe CKD group (n = 95)

χ2, P

Gender (Male/Female)*

271/966

44/138

26/69

1.831, 0.400

Age (y)

51(46, 59)

52(44, 59)

56(47, 61)

4.687, 0.096

25(OH)D (ng/ml)☺

23.80(18.69, 28.92)

20.93(16.83, 25.56)△

19.12(13.83, 24.89)△

49.447, < 0.001

25(OH)D2 (ng/ml)☺

1.77(0.87, 5.38)

2.80(0.94, 6.11)

2.66(0.69, 7.26)

4.713, 0.095

25(OH)D3 (ng/ml)☺

18.50(14.43, 23.73)

16.09(12.93, 21.95)△

13.00(10.60, 20.25)△

51.874, < 0.001

F-25(OH)D (pg/ml)☺

6.03(4.77, 7.81)

5.89(4.60, 6.90)▲

4.87(3.79, 7.05)△

23.512, < 0.001

Cr (µmol/L)

51.1(44.3, 59.7)

57.1(43.0, 75.8)△

105.9(70.7, 133.8)△♀

138.418, < 0.001

CysC (mg/L)

0.93(0.82, 1.07)

1.22(0.95, 1.52)△

1.96(1.63, 2.34)△♀

259.684, < 0.001

eGFR (ml/min/1.73m2)

95.0(83.1, 108.4)

77.1(62.8, 97.5)△

42.3(33.3, 57.3)△

217.965, < 0.001

ACR (mg/g)

6.48(4.07, 11.22)

42.86(30.32, 70.10)△

102.43(30.81, 305.48)△

437.484, < 0.001

hsCRP (mg/L)

12.79(3.27, 35.99)

23.84(8.00, 55.14)

28.13(10.40, 57.30)

45.472, < 0.001

RF (IU/ml)

85.8(14.08, 306.9)

76.5(11.8, 311.0)

142.0(12.2, 347.5)

1.087, 0.581

  1. *The 2 × 3 table χ2 test was used, ☺ the covariance analysis was used, and the others used the Kruskal-Wallis test. After multiple comparisons by Kruskal-Wallis, ▲ represents compared with the Mild CKD group, Padj.<0.05; △ represents compared with the Mild CKD group, Padj.<0.001; ♀ represents compared with the Moderate CKD group, Padj.<0.001.
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