Table 2 Assessment of MIC and MBC of D-form variants (of 1a and 1a-N10-D) in a panel of bacteria*.

From: Rational design of synthetic antimicrobial peptides based on the Escherichia coli ShoB toxin

ID

Sequence

MIC/MBC (µM)

E. coli

S. aureus

K. pneumoniae

A. baumannii

P. aeruginosa

E. faecalis

D-1a

MTDGRYLIKRVKK kkkavlqlilkfl

16/8

32/16

16/16

32/16

16/16

8/16

D-1a-N10

vkkkkkavlqlilkf

2/2

2/2

2/2

8/8

8/16

2/4

  1. *Detection limit:<0.5 µM and > 128 µM.
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