Fig. 3 | Scientific Reports

Fig. 3

From: Differential proteomics of interstitial fluid in lung tissue associated with the progression of pulmonary fibrosis in mice

Fig. 3

Proteomic analysis of the effect of bleomycin on pulmonary fibrosis injury in mice. Protein statistical analysis of pulmonary interstitial fluids in the normal, 7-, 14-, 21-, and 28-day modeling groups. The sample proteins were displayed using (A) differential protein Wayne plots, (B) principal component analysis (PCA), (C) UpSetR plots, and (D) clustering heatmap. The Wayne plot represents differential proteins between different groups, while PCA reflects the overall protein differences between each group of samples and the variability between samples within the group. The clustering heat map represents the up-regulation and down-regulation of different proteins compared between different products(n = 3). (Grouping: (A) normal group, (B) 7-day modeling group, (C) 14-day modeling group, (D) 21-day modeling group, and (E) 28-day modeling group).

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