Fig. 2
From: BPIFB4 rs4339026 A > G polymorphism impacts COPD susceptibility in the Kashi population, China
Results of bioinformatics analysis for BPIFB4. (a) BPIFB4 expression in human peripheral blood. (b) BPIFB4 expression in human BALF. The horizontal axis represented different groups, and the vertical axis represented BPIFB4 expression. The upper left corner represented the statistical test method used to assess significance. *P < 0.05, **P < 0.01. (c) Venn diagram of overlapping proteins associated with both BPIFB4 and COPD. (d) PPI network of overlapping proteins. Circles represented nodes (proteins), and straight lines indicated protein-protein interactions. The size of each node was positively correlated with its degree (the more connections a node had, the higher its degree and the larger its size). The node color was also positively correlated with its degree (the redder the node, the greater its degree; the greener the node, the smaller its degree). (e, f) BPIFB4 participated in key pathways and functional classification in COPD. CC represented cell component, MF represented molecular function, BP represented biological process.
