Fig. 1 | Scientific Reports

Fig. 1

From: Investigating hepatic fibrosis heterogeneity by three-dimensional imaging in metabolic dysfunction-associated steatotic liver disease

Fig. 1

A summary of 3D imaging in cleared liver tissues. (A) The illustration represents the CLARITY method using (B) a non-fibrotic liver tissue, (C) a core liver biopsy, and (D) a cirrhotic liver tissue. (E) Macro configuration of in-house developed LSM and (F) stack image show 3D reconstruction in cleared liver tissue stained against Collagen type I. (Coll-1: Collagen type I; Green, nuclei: Blue) CMOS; Complementary metal-oxide-semiconductor, LSM; Light sheet microscopy. 3D image was created using Leica Application Suite X (Version 3.5.5.19976, URL: https://www.leica-microsystems.com/products/microscope-software/p/leica-las-x-ls/).

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