Fig. 2 | Scientific Reports

Fig. 2

From: Control of motor coordination by transient receptor potential melastatin 8 through γ-aminobutyric acidergic circuit modulation in the male mouse cerebellum

Fig. 2

Effects of transient receptor potential melastatin 8 (TRPM8) deficiency on the rotarod, open field, and footprint tests. (A) Latency to fall off the rotarod in wild-type (WT) and TRPM8-deficient (TRPM8KO) mice. Data are presented as the mean ± standard error (SE) for 9–10 mice per group. *P < 0.05 compared with WT. (B) Distance traveled in the chamber, average movement speed (velocity), and percentage of time spent in the central and peripheral areas in WT and TRPM8KO mice. Data are presented as the mean ± SE for 10 mice per group. *P < 0.05 compared with WT. NS, not significant. (C) Quantification of footprints in terms of stride, sway, and stance in WT and TRPM8KO mice. Data are presented as the mean ± SE for 7 mice per group. NS, not significant.

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