Fig. 11

In silico studies of bis (2-methylheptyl) benzene-1,4-dicarboxylate. (A) The binding pose of Terephthalate (cyano) is depicted with the sclerostin peptide (yellow) on the interacting surface of LRP6 (PDB ID: 3SOV). (B) The binding pose of Terephthalate. 2D-structure interaction poses the essential residues of LRP6 that interact with Terephthalate.