Fig. 1 | Scientific Reports

Fig. 1

From: Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms

Fig. 1

The combination formulation of retinol and CK alleviates the inhibition of photoaging proliferation of HaCaT cells caused by UVA. (A) The chemical structures of ginsenoside CK, retinol (Vitamin A, VA), retinol palmitate (VAPA) and hydroxypinacolone retinoate (HPR); (B) HaCaT cells were irradiated with different doses of UVA ((0, 10, 20, 30, 40, 50 J/cm2), and the effect of UVA irradiation on cell survival rate was detected by MTT method; (C) MTT assay were used to investigate the protective effects of ginsenoside CK alone on the proliferation of HaCaT cells during UVA photoaging. (D–F) MTT assay were used to investigate the protective effects of ginsenoside CK combined with Vitamin A (retinol, 0.01 and 0.02 mg/mL), HPR .(0.05 and 0.1 mg/mL) and retinol palmitate (VAPA, 0.1 and 0.2 mg/mL) on the proliferation of HaCaT cells during UVA photoaging. *P < 0.05; **P < 0.01; ***P < 0.001 versus UVA + DMSO (0.1%) treatment group.

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