Fig. 4 | Scientific Reports

Fig. 4

From: Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms

Fig. 4

The combination of retinol and CK decreased UVA-induced apoptosis of HaCaT cells. (A) The effects of the combination of CK and VA on the expression levels of apoptosis-related proteins were detected by Western Blot. (B) The effects of the combination of CK and HPR on the expression levels of apoptosis-related proteins were detected by Western Blot. (C) The effects of the combination of CK and VAPA on the expression levels of apoptosis-related proteins were detected by Western Blot. Protein expression levels of Caspase 8, Caspase 9 and PARP1 were determined using Western blot analysis in HaCaT cells treated with CK (0.001, 0.005, 0.01 mg/mL) with or without VA (0.01 mg/mL), HPR (0.05 mg/mL) or VAPA (0.1 mg/mL) for 24 h. GAPDH was used as a control protein. Quantification charts were listed on the right. **P < 0.01 vs UVA treatment group. #P < 0.05, ##P < 0.01 versus VA/HPR/VAPA alone treatment group.

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