Fig. 9 | Scientific Reports

Fig. 9

From: Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms

Fig. 9

Ginsenoside CK can reduce the toxicity of retinol in vivo zebrafish. (A) Effects of CK exposure alone (0, 0.01, 0.012, 0.014, 0.016, 0.018, 0.020 mg/mL) for 96 h on hatchability, malformation rate and mortality of zebrafish embryos. (B–D) Effects of VA, HPR, or VAPA exposure alone (0, 0.0004, 0.0006, 0.0008, 0.001, 0.002, 0.004 mg/mL) for 96 h on hatchability, malformation rate and mortality of zebrafish embryos. (E–G) Effects of CK (0, 0.0005, 0.001, 0.002, 0.004, 0.008 mg/mL) combined with VA (0.002 mg/mL), HPR (0.002 mg/mL) or VAPA (0.004 mg/mL) exposure for 96 h on incubation rate, malformation rate and mortality of zebrafish embryos. The results were expressed by means ± standard error (mean ± SEM). Significance analysis was conducted using One-way ANOVA, and P < 0.05 was considered as significant difference. ****P < 0.0001.

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