Fig. 4 | Scientific Reports

Fig. 4

From: Author Correction: Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway

Fig. 4

PI3K agonists attenuate the tumor suppressive effect of Tan-IIA. After the addition of 740y-p (10 µg/mL) to the system in which Tan-IIA (24 h IC50 concentration) and Cholangiocarcinoma cells were co-cultured, the tumor suppressive effect of Tan-IIA was attenuated. (A–E) The inhibitory effect of Tan-IIA on the proliferation of Cholangiocarcinoma cells decreased after the addition of 740y-p. (F–L) The ability of Tan-IIA to inhibit the invasion and migration of Cholangiocarcinoma cells was reduced after the addition of 740y-p. (M–O) The apoptosis-inducing effect of Tan-IIA on Cholangiocarcinoma cells was diminished after 740y-p was added. Compared with control, *p < 0.05; **p < 0.01; ***p < 0.001.

Back to article page