Table 4 Association analysis of HF1A SNPs with clinical and laboratory parameters in IS patients.
From: The association of HIF1A gene polymorphism and its expression with ischemic stroke
Characteristic | rs10873142 | rs11549465 | rs11549467 | ||||
---|---|---|---|---|---|---|---|
CC P | CT P | TT P | CC P | CT P | AG P | GG P | |
Age (years old) | 0.7442 | 0.5533 | 0.4079 | 0.5891 | 0.1382 | 0.7475 | 0.957 |
Gender (male/female) | 0.4777 | 0.0427 | 0.757 | 0.152 | 0.8777 | 0.2824 | 0.0655 |
Height (m) | 0.663 | 0.118 | 0.5989 | 0.1048 | 0.7162 | 0.169 | 0.0448 |
Weight (Kg) | 0.3025 | 0.7833 | 0.7319 | 0.6942 | 0.4763 | 0.3524 | 0.9087 |
Fasting blood-glucose (mmol/L) | 0.5622 | 0.2411 | 0.5663 | 0.1981 | 0.6098 | 0.4848 | 0.391 |
TC (mmol/L) | 0.3132 | 0.0002 | < 0.001 | < 0.001 | 0.4008 | 0.0152 | < 0.001 |
TG (mmol/L) | 0.9578 | 0.8918 | 0.3122 | 0.4922 | 0.5622 | 0.132 | 0.7737 |
HDL-C (mmol/L) | 0.0261 | < 0.001 | < 0.001 | < 0.001 | 0.0255 | 0.3939 | < 0.001 |
LDL-C (mmol/L) | 0.8281 | 0.1093 | 0.315 | 0.0462 | 0.8201 | 0.0411 | 0.1284 |
Apolipoprotein A1 (g/L) | 0.0078 | < 0.001 | < 0.001 | < 0.001 | 0.0014 | 0.0364 | < 0.001 |
Apolipoprotein B (g/L) | 0.8705 | 0.6241 | 0.4628 | 0.405 | 0.862 | 0.026 | 0.6694 |
Blood platelet count (109/L) | 0.028 | 0.7633 | 0.5229 | 0.2172 | 0.2024 | 0.6991 | 0.2011 |
ROS expression | 0.0553 | 0.0174 | 0.0235 | < 0.001 | 0.5237 | 0.3524 | < 0.001 |