Table 4 Association analysis of HF1A SNPs with clinical and laboratory parameters in IS patients.

From: The association of HIF1A gene polymorphism and its expression with ischemic stroke

Characteristic

rs10873142

rs11549465

rs11549467

CC

P

CT

P

TT

P

CC

P

CT

P

AG

P

GG

P

Age (years old)

0.7442

0.5533

0.4079

0.5891

0.1382

0.7475

0.957

Gender (male/female)

0.4777

0.0427

0.757

0.152

0.8777

0.2824

0.0655

Height (m)

0.663

0.118

0.5989

0.1048

0.7162

0.169

0.0448

Weight (Kg)

0.3025

0.7833

0.7319

0.6942

0.4763

0.3524

0.9087

Fasting blood-glucose (mmol/L)

0.5622

0.2411

0.5663

0.1981

0.6098

0.4848

0.391

TC (mmol/L)

0.3132

0.0002

< 0.001

< 0.001

0.4008

0.0152

< 0.001

TG (mmol/L)

0.9578

0.8918

0.3122

0.4922

0.5622

0.132

0.7737

HDL-C (mmol/L)

0.0261

< 0.001

< 0.001

< 0.001

0.0255

0.3939

< 0.001

LDL-C (mmol/L)

0.8281

0.1093

0.315

0.0462

0.8201

0.0411

0.1284

Apolipoprotein A1 (g/L)

0.0078

< 0.001

< 0.001

< 0.001

0.0014

0.0364

< 0.001

Apolipoprotein B (g/L)

0.8705

0.6241

0.4628

0.405

0.862

0.026

0.6694

Blood platelet count (109/L)

0.028

0.7633

0.5229

0.2172

0.2024

0.6991

0.2011

ROS expression

0.0553

0.0174

0.0235

< 0.001

0.5237

0.3524

< 0.001