Fig. 2

Effects of miR-494-3p inhibition in NSCLC cell lines. (A) Expression of miR-494-3p in 17 NSCLC cell lines and two immortalized lung epithelial cell lines. Cell lines were color-coded (black = mutated, white = wild) to indicate mutational status of EGFR, KRAS, and TP53. (B) Cell viability, (C) migration, (D) invasion assay, and (E) miR-494-3p expression levels in NCI-H2030, DFCI024, and NCI-H647 cells treated with miR-494-3p AS (AS). P values were calculated using unpaired t-test. Columns indicate average of triplicate samples from a representative experiment. Bars indicate standard deviation (SD). AS, miR-494-3p AS.